Profile For Rob R.

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    6 years, 11 months ago

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Posted:  6 years, 11 months ago

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PLEASE help drug test question...

Xanax is a Benzodiazepine with a half life of about 12 Hours and can vary +- few hours based on the biology of the person. This means that if you took .5 mg of Xanax after 12 hours you would have roughly .25 mg after 24 hours 12.5 mg and so on... It takes roughly 4-6 half-lives for blood levels drop to virtually 0 for Xanax this equates to 2-3 days, usually depending on dosage. It’s hard to say whether his urine will test positive for Benzodiazepines after only one day, it really depends on how much he took in the first place. I would like to point out that urine tests do not tend to be as sensitive as blood samples; in other words, just because there is still a testable level in the blood doesn't necessarily mean a positive urine test, meaning there is a chance for urine to test negative when there is still drugs in the system. Of course this probably isn't always true and only happens on extremely low blood levels of the drug. I do not know for sure (somebody correct me if I am wrong) but as far as I know, testing for Benzodiazepines is not required by DOT, so you may be in the clear here but this doesn't mean your particular company doesn't test for it. Also just for future reference a lot of “sleeping pills” prescribed by doctors are benzodiazepines (i.e. Ativan, Klonipin, Xanax). On the other hand you have Z-drugs or non-benzodiazepines sleep aids such as Ambien; these too can be tested for and I've heard (only anecdotally) that some companies aren't keen on sleeping issues, which gives them a reason to test for it (not sure if they do test for it, but seems to be a possibility). As far as I’m concerned there isn't a whole lot of difference between Z-drugs and Benzodiazepines (hence the reason they are also referred to as Benzodiazepine-like drugs) as they both work on GABA Receptors (GABA being the main inhibitory neurotransmitter in the brain), although they do have the advantage of a shorter half-life (2-3 hours) and a high affinity for only the GABA Aa1 receptor related to the hypnotic and amnesia effect (which in actuality I believe the be the most dangerous effects out of the other 3 effects[Muscle relaxant, anti anxiety, anticonvulsant,] related to the other 5 subunits [a2-a6]). For this reason I believe it is always in your best interest to find out more information about any drug before taking it when possible (this is just my opinion and should be taken as such, as I am not a doctor; As always you should talk to your doctor to get their professional opinion on making these decisions). And as a last word to the wise, never ever take un-prescribed drugs as that now becomes a legal issue or at least becoming pinned as a drug abuser.

P.S. I'm not sure if this is an embarrassingly long post for my first one, but i enjoy being helpful ;-)

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